FAN Hong-li, CHEN Mei-feng, MENG De-su. Catalyst-free and Solvent-free Synthesis of 2-Phenylimidazo1,2-apyridinesJ. Journal of Xinyang Normal University (Natural Science Edition), 2012, 25(3): 371-373.
Citation: FAN Hong-li, CHEN Mei-feng, MENG De-su. Catalyst-free and Solvent-free Synthesis of 2-Phenylimidazo1,2-apyridinesJ. Journal of Xinyang Normal University (Natural Science Edition), 2012, 25(3): 371-373.

Catalyst-free and Solvent-free Synthesis of 2-Phenylimidazo1,2-apyridines

  • 2-phenylimidazo1,2-apyridines were synthesized via the condensation reaction of 2-bromoacetophenone and 2-aminopyridine under the conditions of catalyst-free and solvent-free with yields of 55.0 % ~ 90.0 %.The structures of the products were characterized by 1 H NMR,IR and MS techniques.The proposed technique has the advantages of mild reaction conditions,simplicity,and environment-friendly.
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