无溶剂条件下硅胶固载硫酸催化酮与芳香醛的Cross-Aldol缩合反应
Silicon Dioxide Supported Sulfuric Acid as an Efficient Catalyst for Cross-Aldol Condensation of Ket
-
摘要: 在无溶剂条件下,用硅胶(mSiO2·nH2O)固载硫酸催化环己酮与芳香醛的Cross-Aldol缩合反应.结果表明,反应时间60～150 min,产率可达72%～93%,共得到5个相应的α,β-不饱和羰基化合物.该方法操作简单,催化剂可重复使用,且对环境友好.Abstract: Aromatic aldehydes underwent cross-aldol condensation with ketones in the presence of silicon dioxide supported sulfuric acid under solvent-free conditions to afford 7 corresponding α,β-unsaturated ketones,in shrot reaction time(50～150 min) and good yields(72%～93%).This method provides a synthetic method with simple work-up procedure,reusing of catalyst,and environment benign.
下载: