Abstract: The ANGPTLs is one of secret protein factors,which was found recently and related with lipid metabolism,glucose metabolism and genesis of blood vessel.The ANGPTLs play an important role on the clearance of blood plasma,lipolysis of adipose tissue and occurrence of obesity.Research progress of basic structure,relationship with energy metabolism and regulation of these gene expression for ANGPTLs gene were summarized in this paper and prospect of treating blood disease,obesity and hyperlipidaemia for ANGPTLs ...