Abstract: Three different enzymes are involved in lignin degradation produced by the white rot fungi, they are lignin peroxidases, manganese peroxidases and laccase. Laccase is a kind of Cu-contained polyphenol oxidizes which are being widely studied recently, it is produced by many white rot fungi and some advanced plant. Some characteristics of the laccase are also detailed. Laccase can oxidize about 250 substances, the Cu-contained areas are very important in its oxidize process. More than 20 laccase gene of diffe...