Abstract: Aim to address the issues of the current tedious extracted technology of tea saponins from Camellia oleifera cake and obtain highly pure tea saponins, The soxhlet extraction, ultrasonic-assisted alcohol extraction, macroporous resin column chromatography, alcohol precipitation and recrystallization were employed.The effects of factors such as extraction temperature, separation fillers and chromatographic conditions, solvent and precipitation conditions, crystallization conditions were investigated. The results demonstrated that the optimal extract process is as follows: Using 80% ethanol to extract the cake at room temperature, and then freezing the resulting solution to remove the oil layer, subsequently, macroporous resin HP-20 was employed to purify the extraction, the 80% ethanol/water fraction was collected. After that, this fraction was concentrated and recrystallized at low-temperature, ultimately yielding high-purity tea saponin samples devoid of any pigments after lyophilization.