Abstract: Based on the dynamic model of the laterally loaded partially-embedded single pile, the finite difference method is used to achieve accurate modeling of the soil-structure interaction (SSI) system, and to solve the natural frequencies of the single pile affected by scour. Then Green's function is used to solve the analytical solutions of forced vibration of the single pile and reveal the changes in lateral dynamic characteristics of the single pile under scour. Through numerical calculation and parameter analysis, the effect of the soil's characteristics and pile's slenderness on the lateral dynamic characteristics of the single pile affected by scour are studied. As the scour degree intensifies, the frequencies of each order of the pile foundation are significantly reduced. The first-order frequency of the pile foundation decreases with the increase of the slenderness of the pile, and the variation law of the higher-order frequencies is complex. The frequencies of each order of pile foundation increase with the increase of elastic modulus of soils. If the elastic modulus of soils increases by one time (or four times), the first-order frequency of pile foundation increases by about 20% (or 40%).