Abstract: In order to solve the problem of multi-layer interference caused by D2D communication multiplexing channel resources in heterogeneous cellular networks, a D2D communication resource allocation strategy based on simultaneous wireless information and power transfer (SWIPT) is proposed to alleviate the interference in the system and maximize the energy efficiency of the D2D link. Firstly, the various interferences in the system are formulated, an interference graph and a set of partner candidates are constructed. Then, the optimization problem is transformed into two sub-problems of power control and channel allocation, and the KKT condition and the Lagrange multiplier method are used to solve the optimal transmit power and power split ratio of the sub-channels in the candidate set of D2D link multiplexing. The experimental results show that the proposed strategy can effectively improve the energy efficiency of the system and D2D user access rate under the premise of ensuring cellular user QoS.