Abstract: N-butyl levulinate is produced from biomass-derived furfuryl alcohol by using the extremely low acid as catalyst system. The effects of reaction temperature, reaction time, amount of catalyst and their interaction on the yield of n-butyl levulinic acid are studied by response surface method. The reaction conditions for the formation of n-butyl levulinic acid from furfuryl alcoholare optimized. The optimum processing conditions are as follows: the reaction temperature is 150℃, the reaction time is 3.0 h, the concentration of sulfuric acid is 0.008 6 mol/L. Under the optimum conditions, the yield of n-butyl levulinate is 73.32%.