Abstract: The bibliometric and knowledge graph analysis is completed with the visual tools based on published data of Journal of Xinyang Normal University(Natural Science Edition) in 40 years (1981-2020). The results show that: (1) The number of papers has shown trends of "overall growth-overall stability".Then the permanent columns include basic theoretical research, applied technology research, review comment and contention. (2) The authors and their affiliated institutions have shown a centralized trend, and multiple core author groups such as "CHEN Yanguang" "LI Hongjing" "YANG Xingkun" "DAI Qirun" have been preliminarily formed. The publishing institutions are mainly normal universities in the central region of China, showing a "double centralized" trend of "central" and "normal" universities; (3) The centrality and frequency of keywords show a certain linear relationship, some core keywords are "synthesis, adsorption and stability"(chemistry), "Henan Province, fractal and fractal dimension"(geography), "stability, time-lag"(mathematics) and "adsorption, spectrophotometry and bentonite"(environment). The citation bursts show good periodicity and continuity, and the highly cited literature meets the "pareto principle"; (4) University journals play an important role in talent construction and discipline training. The bibliometric and knowledge graph analysis of university journals can provide some reference for the future development trend of journals.