Abstract: MOF-La was synthesized by hydrothermal method, and the MOF-La with flower structure was obtained by using of NaOH solution. The surface structure and morphology were characterized by X-ray diffraction, specific surface and aperture analyzer and scanning electron microscopy (SEM).The equilibrium concentration of phosphate in the water was measured by UV-visible spectrophotometer (UV-vis). The structure and properties of MOF-La were analyzed. The conclusions are as follows: (1) MOF-La has good water stability; (2) The adsorption capacity of MOF-La with flower structure for phosphate was 24.4 mg/g; (3) The kinetics of phosphate adsorption of MOF-La with flower structure can be fitted by the pseudo-second-order kinetic model. The data for phosphate adsorption of MOF-La with flower structure can be described by Langmuir and Freundlich isotherm adsorption models.