Abstract: Parkinson's disease (PD) is a common neurodegenerative disorder. Tea contains specific polyphenols which can play an important role in delaying the onset or halting the progression of PD. Numerous in vitro studies indicated that tea polyphenols play neuroprotective roles in PD through anti-oxidant, iron-chelating properties, inhibition of α-synuclein aggregation and modulation of intracellular signalling pathways.The neuroprotection of tea polyphenols in animals of PD models and clinical trials were reviewed,and suggestion for the existing problems and developmental trend of tea polyphenols agsinst PD were provided.