Abstract: In order to obtain a more effective assessment results on durability of highway concrete, a new method of fuzzy comprehensive evaluation based on life cycle theory was established, which combined life cycle theory and fuzzy comprehensive evaluation, and the durability evaluation of highway concrete was proposed by analyzing promoting and deteriorating factors. The specific implementary process of the method was analyzed through by taking the durability assessment of a practical engineering as an example. It brings forward a new way of thinking to make assessment of concrete durability effectively.