Abstract: Groundwater encroachment leads to the frequent occurrence of tunnel seepage disease. It is an important issue to select effective treatment scheme for tunnel seepage treatment. Considering the uncertainty of evaluation factors of tunnel seepage control, the cloud model and TOPSIS evaluation method are combined to eliminate the influence of subjective factors on seepage control evaluation. Based on a large number of engineering practices and existing research results, the evaluation index system of seepage management in operating tunnels is constructed, including four first-level evaluation indexes of technical adaptability, environmental adaptability, economic adaptability and social adaptability, corresponding to 16 secondary evaluation indicators of leakage water treatments program. According to the monitoring data of leakage water in the sensitive section of Wangjiawan in Wuhan City, the five alternative water leakage treatment schemes of surface plugging method, waterproof plate waterproof method, spray plugging method, grouting treatment method and waterproof gasket method are proposed. The cloud model TOPSIS is used for evaluation and selection, and the grouting treatment method is determined as the optimal solution, which is applied to the evaluation of the leakage treatment scheme for operating subway tunnels.